CODE EXAMPLE FOR TYPESCRIPT

based on previous make validation for required in reactive forms

this.userCustomForm.get('age').valueChanges.subscribe(val => {
  if (condition) {
    this.userCustomForm.controls['licenseNo'].setValidators([Validators.required]);
  } else {
    this.userCustomForm.controls['licenseNo'].clearValidators();
  }
  this.userCustomForm.controls['licenseNo'].updateValueAndValidity();
});