from selenium import webdriver
from selenium.webdriver.common.by import By
from selenium.webdriver.support.ui import WebDriverWait
from selenium.webdriver.support import expected_conditions as EC
driver = webdriver.Chrome()
driver.get(url)
# wait(at least 10 seconds) for element will be clickable and clcick on it
WebDriverWait(driver, 20).until(EC.element_to_be_clickable((By.XPATH, "//a[@class = 'playButton']"))).click();