>>> string = "Hello World"
>>> # Check Sub-String in String
>>> "World" in string
True
>>> # Check Sub-String not in String
>>> "World" not in string
False
mystring = ["reddit", "google"]
mylist = ["a", "b", "c", "d"]
print [s for s in mystring if not any(x in s for x in mylist)]
str = '£35,000 per year'
# check for '£' character in the string
'£' not in str
# >> False
'£' in str
# >> True