# python 3.x
import pandas as pd
import numpy as np
df = pd.DataFrame(data=np.random.randint(0, 10, (6,4)))
df.columns=["a", "b", "c", "d"]
print(df)
Cov = pd.read_csv("path/to/file.txt",
sep=' ',
names=["Sequence", "Start", "End", "Coverage"])