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python remove second occurrence of character in string

import re 
#Remove the second Hello from example

example = "Hello, world. Hello!" 
print re.sub(r'^((.*?Hello.*?){1})Hello', r'1Goodbye', str) 
# Prints "Hello, world. Goodbye!"

#To remove any particular occurance adjust the {1} to the desired number

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python remove second occurrence of character in string

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