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pandas rename multiple columns

# df is a pandas DataFrame

for col_name in df.columns:
  # you can specify conditions if you need 
  # to change the name of some column only
  df = df.rename(columns = {col_name:new_col_name}
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renaming multiple columns in pandas

[df.rename(columns={df.columns[j]: COLUMNS[j]}, inplace=True) for j in range(df.shape[1])]
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rename multiple value in column in pandas

df['column name'] = df['column name'].replace(['1st old value','2nd old value',...],'new value')
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